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Table 2 Coefficients of the 12 features in the Drug-EvoD model.

From: Evolutionary Diagnosis of non-synonymous variants involved in differential drug response

Parameter

Species

Coefficient

 

Primates-only

12.2

Evolutionary Rate

Mammals-only

22.3

 

All-species

-29.5

 

Primates-only

ns

Evolutionary Timespan (Position)

Mammals-only

ns

 

All-species

12.1

 

Primates-only

ns

Evolutionary Timespan (Variant)

Mammals-only

21.8

 

All-species

-19.9

 

Grantham Value

-9.8

Others

Blosum62

-11.6

 

Entropy2

ns

  1. Note –Features that were removed in the feature selection step are indicated by ns.