Figure 3From: Combined analysis of gene regulatory network and SNV information enhances identification of potential gene markers in mouse knockout studies with small number of samplesComparison of the number of the gene marker candidates between non-filtered and filtered method in NF-kappa B signaling pathway. (A) NF-kappa B signaling pathway mapped with non-filtered candidates. With no filtering method, too many genes are shown in the pathway which makes it difficult to find an appropriate gene marker. (B) NF-kappa B signaling pathway mapped with candidates filtered by DEG. The number of genes is greatly reduced compared to the non-filtered method. However, difficulty exists in finding significant gene marker as the number of genes are still too many. (C) NF-kappa B signaling pathway mapped with full-filtered candidates. The number of genes was greatly reduced compared to the non-filtered or DEG-only filtered candidates while keeping the genes reported by Yagi et al.(2013).Back to article page