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Table 1 Average number of protein sequences misclassified (out of 14,086 testing sequences from COG [6] database) by the different protein classification methods.

From: Graph pyramids for protein function prediction

max bit-score

362.3

max EB-score

263.2

sum bit-score

587.5

sum EB-score

238.1

mean bit-score

970.0

mean EB-score

308.4

T R without GP

1404

T R with GP hierarchy

150.7

KNN classifier

309.7

Highest scoring BLAST match [2]

362.9

Boujenfa et al. (using ClustalW) [27]

35.2

Proposed majority voting of GSF (No Hie)

28.2

Proposed GP based hierarchical voting (GP Hie)

21.1