Skip to main content

Table 1 Top diseases and drugs with a large degree in the bipartite drug-disease network

From: Inferring drug-disease associations based on known protein complexes

Disease Name Number of direct neighbors Sum of weight on edges Drug ID Drug name Number of directed edges Sum of weight on edges
Mental disorders 51 39.58 DB00098 Antithymocyte globulin 27 19.90
Cystic fibrosis 33 18.56 DB01259 Lapatinib 18 15.07
Primary biliary cirrhosis 30 20.28 DB08916 Afatinib 17 13.79
Attention deficit hyperactivity disorder 26 16.40 DB00054 Abciximab 16 13.49
Anorexia nervosa 25 17.14 DB00775 Tirofiban 15 15.31
Panic disorder 25 16.77 DB00072 Trastuzumab 12 9.13
Sudden infant death syndrome 25 18.27     
Epilepsy 24 13.37     
Hypertension 24 13.26     
Migraine 21 11.10     
Supranuclear palsy, progressive 21 11.51     
Mucocutaneous lymph node syndrome 11 8.45     
Subacute sclerosing panencephalitis 10 5