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Table 2 Drug-mental disorders associations (weight ≥ 0.5)

From: Inferring drug-disease associations based on known protein complexes

ID

Drug ID

Drug Name

Weight

ID

Drug ID

Drug Name

Weight

1

DB00904

Ondansetron

0.89

27

DB00334

Olanzapine

0.82

2

DB00669

Sumatriptan

0.85

28

DB01186

Pergolide

0.82

3

DB00734

Risperidone

0.73

29

DB01618

Molindone

0.82

4

DB00490

Buspirone

0.77

30

DB06684

Vilazodone

0.82

5

DB01149

Nefazodone

0.93

31

DB01621

Pipotiazine

0.82

6

DB01142

Doxepin

0.83

32

DB01616

Alverine

0.82

7

DB01392

Yohimbine

0.87

33

DB01200

Bromocriptine

0.82

8

DB00540

Nortriptyline

0.89

34

DB00216

Eletriptan

0.81

9

DB01224

Quetiapine

0.82

35

DB01622

Thioproperazine

0.79

10

DB00363

Clozapine

0.82

36

DB01614

Acepromazine

0.79

11

DB00477

Chlorpromazine

0.78

37

DB00960

Pindolol

0.77

12

DB00571

Propranolol

0.75

38

DB04946

Iloperidone

0.76

13

DB00321

Amitriptyline

0.69

39

DB08807

Bopindolol

0.75

14

DB00726

Trimipramine

0.90

40

DB08815

Lurasidone

0.75

15

DB00247

Methysergide

0.87

41

DB06216

Asenapine

0.74

16

DB00656

Trazodone

0.86

42

DB01049

Ergoloid mesylate

0.74

17

DB00315

Zolmitriptan

0.85

43

DB05271

Rotigotine

0.72

18

DB00952

Naratriptan

0.85

44

DB01267

Paliperidone

0.72

19

DB08810

Cinitapride

0.84

45

DB01359

Penbutolol

0.60

20

DB00589

Lisuride

0.84

46

DB00866

Alprenolol

0.60

21

DB00268

Ropinirole

0.84

47

DB00696

Ergotamine

0.56

22

DB00413

Pramipexole

0.84

48

DB00998

Frovatriptan

0.55

23

DB00714

Apomorphine

0.83

49

DB00918

Almotriptan

0.55

24

DB00248

Cabergoline

0.83

50

DB00953

Rizatriptan

0.53

25

DB01238

aripiprazole

0.82

51

DB00320

Dihydroergotamine

0.50

26

DB00246

ziprasidone

0.82

    
  1. Drug ID represents the unique DrugBank accession number of a drug. Drug Name represents the corresponding name of a Drug ID. Weight represents the correlation between a drug and the mental disorder. 40 drugs are approved by our benchmark, 9 predicted drugs are supported by literature (in bold italic), and 2 are not directly supported by the literatures (in underlined bold).