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Table 2 Drug-mental disorders associations (weight ≥ 0.5)

From: Inferring drug-disease associations based on known protein complexes

ID Drug ID Drug Name Weight ID Drug ID Drug Name Weight
1 DB00904 Ondansetron 0.89 27 DB00334 Olanzapine 0.82
2 DB00669 Sumatriptan 0.85 28 DB01186 Pergolide 0.82
3 DB00734 Risperidone 0.73 29 DB01618 Molindone 0.82
4 DB00490 Buspirone 0.77 30 DB06684 Vilazodone 0.82
5 DB01149 Nefazodone 0.93 31 DB01621 Pipotiazine 0.82
6 DB01142 Doxepin 0.83 32 DB01616 Alverine 0.82
7 DB01392 Yohimbine 0.87 33 DB01200 Bromocriptine 0.82
8 DB00540 Nortriptyline 0.89 34 DB00216 Eletriptan 0.81
9 DB01224 Quetiapine 0.82 35 DB01622 Thioproperazine 0.79
10 DB00363 Clozapine 0.82 36 DB01614 Acepromazine 0.79
11 DB00477 Chlorpromazine 0.78 37 DB00960 Pindolol 0.77
12 DB00571 Propranolol 0.75 38 DB04946 Iloperidone 0.76
13 DB00321 Amitriptyline 0.69 39 DB08807 Bopindolol 0.75
14 DB00726 Trimipramine 0.90 40 DB08815 Lurasidone 0.75
15 DB00247 Methysergide 0.87 41 DB06216 Asenapine 0.74
16 DB00656 Trazodone 0.86 42 DB01049 Ergoloid mesylate 0.74
17 DB00315 Zolmitriptan 0.85 43 DB05271 Rotigotine 0.72
18 DB00952 Naratriptan 0.85 44 DB01267 Paliperidone 0.72
19 DB08810 Cinitapride 0.84 45 DB01359 Penbutolol 0.60
20 DB00589 Lisuride 0.84 46 DB00866 Alprenolol 0.60
21 DB00268 Ropinirole 0.84 47 DB00696 Ergotamine 0.56
22 DB00413 Pramipexole 0.84 48 DB00998 Frovatriptan 0.55
23 DB00714 Apomorphine 0.83 49 DB00918 Almotriptan 0.55
24 DB00248 Cabergoline 0.83 50 DB00953 Rizatriptan 0.53
25 DB01238 aripiprazole 0.82 51 DB00320 Dihydroergotamine 0.50
26 DB00246 ziprasidone 0.82     
  1. Drug ID represents the unique DrugBank accession number of a drug. Drug Name represents the corresponding name of a Drug ID. Weight represents the correlation between a drug and the mental disorder. 40 drugs are approved by our benchmark, 9 predicted drugs are supported by literature (in bold italic), and 2 are not directly supported by the literatures (in underlined bold).