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Table 3 Drug-hypertension associations (weight ≥ 0.5)

From: Inferring drug-disease associations based on known protein complexes

ID Drug ID Drug Name Weight ID Drug ID Drug Name Weight
1 DB06216 Asenapine 0.71 17 DB00413 Pramipexole 0.52
2 DB00571 Propranolol 0.66 18 DB00589 Lisuride 0.52
3 DB08807 Bopindolol 0.66 19 DB01149 Nefazodone 0.52
4 DB00960 Pindolol 0.64 20 DB00247 Methysergide 0.52
5 DB00866 Alprenolol 0.59 21 DB01049 Ergoloid mesylate 0.52
6 DB01359 Penbutolol 0.59 22 DB00714 Apomorphine 0.52
7 DB01200 Bromocriptine 0.54 23 DB00656 Trazodone 0.51
8 DB00248 Cabergoline 0.54 24 DB01142 Doxepin 0.50
9 DB00246 Ziprasidone 0.53 25 DB00904 Ondansetron 0.50
10 DB00334 Olanzapine 0.53 26 DB08815 Lurasidone 0.50
11 DB01238 Aripiprazole 0.53 27 DB00216 Eletriptan 0.50
12 DB00363 Clozapine 0.53 28 DB00734 Risperidone 0.50
13 DB01224 Quetiapine 0.53 29 DB00726 Trimipramine 0.50
14 DB01186 Pergolide 0.53 30 DB04946 Iloperidone 0.50
15 DB01392 Yohimbine 0.52 31 DB01267 Paliperidone 0.50
16 DB00268 Ropinirole 0.52     
  1. Drug ID represents the unique DrugBank accession number of a drug. Drug Name represents the corresponding name of a Drug ID. Weight represents the value of correlation between a drug and the mental disorders. 26 drugs are approved by our benchmark. Among the remaining 5 drugs, 4 (in bold italic) have negative relationships with the mental disorders and 1 (in underlined bold) has a positive relationship with the mental disorders.