Inferring drug-disease associations based on known protein complexes

BMC Medical Genomics

Table 4 Correlations of twenty-six Drugs with hypertension

ID	Drug ID	Drug Name	Correlation (CTD, N, or Unknown)	ID	Drug ID	Drug Name	Correlation (CTD, N, or Unknown)
1	DB00315	Zolmitriptan[60]	N	14	DB01622	Thioproperazine	Unknown
2	DB00476	Duloxetine[61]	N	15	DB06701	Dexmethylphenidate	Unknown
3	DB04896	Milnacipran[56]	N	16	DB08810	Cinitapride	Unknown
4	DB06204	Tapentadol[62]	N	17	DB01363	Ephedra [55]	N
5	DB06684	Vilazodone[63]	N	18	DB00472	Fluoxetine	CTD
6	DB06700	Desvenlafaxine [57]	N	19	DB00176	Fluvoxamine	CTD
7	DB08918	Levomilnacipran [64]	N	20	DB00543	Amoxapine	CTD
8	DB00805	Minaprine	Unknown	21	DB01104	Sertraline	CTD
9	DB00952	Naratriptan	Unknown	22	DB06148	Mianserin	CTD
10	DB00998	Frovatriptan	Unknown	23	DB01577	Methamphetamine	CTD
11	DB01614	Acepromazine	Unknown	24	DB01151	Desipramine	CTD
12	DB01616	Alverine	Unknown	25	DB00852	Pseudoephedrine	CTD
13	DB01621	Pipotiazine	Unknown	26	DB00514	Dextromethorphan	CTD

Drug ID represents the unique DrugBank accession number of a drug. Drug Name represents the corresponding name of a Drug ID. There are three types of correlation: (a) CTD represents the drug-hypertension correlation that can be found in the CTD database; (b) N represents the drug-hypertension correlation that may be negative, supported by literature; (c) Unknown means that there is no evidence suggesting the drug-hypertension relation as yet.

ISSN: 1755-8794