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Table 1 HCC cell lines and their correlations with tumors.

From: Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research

Cell Line Correlation (P value) Sex Ethnicity/Race Age Known cancer etiology or other characteristics
HepG2 0.55 (3.4E-4) M Caucasian/NA 15 No evidence of a Hepatitis B virus genome
C3A 0.53 (1.1E-3) M Caucasian/NA 15 No evidence of a Hepatitis B virus genome; derivative of HepG2
huH-1 0.52 (1.9E-3) M Asian/Japanese 53 HBs-antigen carrier
JHH-5 0.51 (3.3E-3) M Asian/Japanese 50 Small liver cancer observed in the chronic hepatitis; integration of the HBV-DNA was not observed
SNU-878 0.51 (3.3E-3) F Asian/Korean 54 One of newer cell lines in the SNU series
SNU-761 0.5 (5.5E-3) M Asian/Korean 49 One of newer cell lines in the SNU series
HuH-7 0.49 (8.8E-3) M Asian/Japanese 57 Well differentiated hepatocellular carcinoma
SNU-886 0.48 (1.4E-2) M Asian/Korean 57 One of newer cell lines in the SNU series
JHH-7 0.47 (2.1E-2) M Asian/Japanese 53 HBs-Ag positive hepatocellular carcinoma with liver cirrhosis
PLC/PRF/5 0.47 (2.1E-2) M NA 24 Malignant liver cancer with HBsAg positive
Alexander cells 0.46 (3.1E-2) M NA 24 Malignant liver cancer with HBsAg positive
Hep 3B2.1-7 0.46 (3.1E-2) M Black/NA 8 Hepatitis B virus DNA was detected
Li-7 0.46 (3.1E-2) NA NA NA NA
JHH-2 0.45 (4.5E-2) M Asian/Japanese 57 Integration of the HBV-DNA was not observed
SNU-387 0.44 (0.06) F Asian/Korean 41 Patient treated by transcatheter arterial embolization with lipoidol plus a combination of doxorubicin and mitomycin-C
SNU-475 0.42 (0.12) M Asian/Korean 43 Taken from a patient prior to cytotoxic therapy
JHH-4 0.42 (0.12) M Asian/Japanese 51 HBs antigen-negative; HCV was not detected
JHH-1 0.41 (0.16) M Asian/Japanese 50 Complication of hepatic cirrhosis and hepatocellular carcinoma
SNU-449 0.41 (0.16) M Asian/Korean 52 Hepatitis B virus DNA was detected; taken from a patient prior to cytotoxic therapy
JHH-6 0.39 (0.25) F Asian/Japanese 57 HBV-DNA was not integrated; undifferentiated hepatocellular carcinoma
SNU-423 0.36 (0.44) M Asian/Korean 40 Hepatitis B virus DNA was detected; treated by transcatheter arterial embolization with lipoidol plus doxorubicin
SNU-182 0.35 (0.51) M Asian/Korean 24 Taken from a patient prior to cytotoxic therapy
HLF 0.33 (0.64) M NA 68 Hepatoma, non-differentiated
HLE 0.32 (0.70) M NA 68 Hepatoma, non-differentiated
SNU-398 0.28 (0.89) M Asian/Korean 42 Hepatitis B virus (HBV) DNA was detected; treated by transcatheter arterial embolization with lipoidol plus a combination of doxorubicin and mitomycin-C
  1. Median of correlation coefficients is used.