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Figure 2 | BMC Medical Genomics

Figure 2

From: Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles

Figure 2

Gene differential expression in t-AML compared with controls. A) Significantly differentially expressed genes in t-AML when compared with normal HSC+ cells (Q-value<0.05). B) Significantly differentially expressed genes in -7/del7q t-AML when compared with normal HSC+ cells (Q-value<0.05). C) The significantly up-regulated (red) or down-regulated (blue) genes in −7/del7q t-AML, residing on chromosome 7. The non-significant genes are in gray. The HOX family genes in 7p15.2 consist of both up- and down-regulated genes.

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BMC Medical Genomics

ISSN: 1755-8794

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