Table 2 Three functional and transcriptional biomodules.
MsigDB definition | Fisher's exact test | ||||||
|---|---|---|---|---|---|---|---|
Gene-set | Category | Description | Pubmed | Size | P | OR | # |
YOSHIMURA_MAPK8_TARGETS_UP | CGP | Genes up-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) | 16311603 | 1305 | 1.6e-5 | 5.0 | 13 |
TATAAA_V$TATA_01 | Motif | Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TATAAA which matches annotation for TAF TATA | NA | 1296 | 4.6e-4 | 3.7 | 12 |
NUYTTEN_EZH2_TARGETS_UP | CGP | Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 by RNAi. | 17724462 | 1037 | 1.1e-3 | 4.0 | 9 |