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Table 1 Characteristic of the three subject groups on important clinical variables related to cocaine use.

From: Refining multivariate disease phenotypes for high chip heritability

Variable Group1
250(14.27)
Group2
339(19.35)
Group3
926(52.85)
Group4
237(13.53)
Tolerance to cocaine 124(49.60) 80(23.60) 807(87.15) 123(51.90)
Withdrawal from cocaine 14(5.60) 275(81.12) 813(87.80) 192(81.01)
Using cocaine in larger amounts or over longer period than intended 249(99.60) 323(95.28) 816(88.12) 103(43.46)
Persistent desiring or unsuccessful cutting down cocaine use 223(89.20) 326(96.17) 839(90.60) 233(98.31)
Great amount of time spent in activities related to cocaine 240(96.00) 290(85.55) 823(88.88) 82(34.60)
Gave up or reduced important activities because of cocaine use 170(68.00) 212(62.54) 806(87.04) 156(65.82)
Cocaine use despite knowledge of problems likely caused by cocaine 209(83.60) 315(92.92) 817(88.23) 170(71.73)
Number of CD criteria endorsed 4.92(1.07) 5.37(1.08) 6.18(2.10) 4.47(1.50)
Age when first used cocaine 21.93(6.34) 22.32(6.51) 21.44(5.75) 22.97(8.42)
Age onset of DSM4 cocaine dependence 28.24(7.88) 28.31(7.95) 26.63(6.70) 28.32(8.06)
Transition time in years from first cocaine use to first CD diagnosis 8.01(12.05) 8.07(12.91) 12.15(21.30) 15.19(24.65)
  1. N (%) is shown for the first seven binary variables, where N is the number of subjects who are positive on the corresponding variable within a group and % is the percentage of N in the group.
  2. µ(σ2) is shown for the last four continuous variable, where µ is the group mean and σ2 the standard deviation.