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Table 2 Prediction performance comparisons between Bcell-HCV and representive methods using the BR-HCV dataset.

From: Prediction of linear B-cell epitopes of hepatitis C virus for vaccine development

Methods Cross-validation on the
BR-HCVTr dataset
Independent test on the
BR-HCVTe dataset
  SP SE AUC MCC ACC SP SE AUC MCC ACC
Bcell-HCV (this study) 0.864 0.731 0.97 0.596 79.6% 0.764 0.651 0.76 0.417 70.7%
SVM-PCP 0.903 0.862 0.95 0.766 87.9% 0.589 0.721 0.74 0.313 66.5%
SVM-AAC 0.870 0.797 0.99 0.662 83.1% 0.620 0.709 0.76 0.331 66.5%
SVM-DPC 0.934 0.889 0.98 0.811 90.5% 0.616 0.713 0.74 0.331 66.5%
SVM-TPC 0.948 0.895 0.96 0.831 91.5% 0.078 0.992 0.73 0.173 49.9%
LBtope (SVM) - - - - - 0.162 0.841 - -0.042 49.9%
ABCPred (ANN) - - - - - 0.823 0.166 - -0.015 49.4%