Table 2 Prediction performance comparisons between Bcell-HCV and representive methods using the BR-HCV dataset.
From: Prediction of linear B-cell epitopes of hepatitis C virus for vaccine development
Methods | Cross-validation on the BR-HCVTr dataset | Independent test on the BR-HCVTe dataset | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | SP | SE | AUC | MCC | ACC | SP | SE | AUC | MCC | ACC |
Bcell-HCV (this study) | 0.864 | 0.731 | 0.97 | 0.596 | 79.6% | 0.764 | 0.651 | 0.76 | 0.417 | 70.7% |
SVM-PCP | 0.903 | 0.862 | 0.95 | 0.766 | 87.9% | 0.589 | 0.721 | 0.74 | 0.313 | 66.5% |
SVM-AAC | 0.870 | 0.797 | 0.99 | 0.662 | 83.1% | 0.620 | 0.709 | 0.76 | 0.331 | 66.5% |
SVM-DPC | 0.934 | 0.889 | 0.98 | 0.811 | 90.5% | 0.616 | 0.713 | 0.74 | 0.331 | 66.5% |
SVM-TPC | 0.948 | 0.895 | 0.96 | 0.831 | 91.5% | 0.078 | 0.992 | 0.73 | 0.173 | 49.9% |
LBtope (SVM) | - | - | - | - | - | 0.162 | 0.841 | - | -0.042 | 49.9% |
ABCPred (ANN) | - | - | - | - | - | 0.823 | 0.166 | - | -0.015 | 49.4% |