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Figure 3 | BMC Medical Genomics

Figure 3

From: Multiple target drug cocktail design for attacking the core network markers of four cancers using ligand-based and structure-based virtual screening methods

Figure 3

DNA damage_ATM/ATR regulation of G1/S checkpoint. It is the highest scoring map (i.e., the map with the lowest p value). ATM/ATR regulates both the checkpoints of the G1/S and S/G2. DNA damage checkpoints pathways arrest or delay the progression of cell cycle in response to the DNA damage. Eukaryotic cell cycle have four phases, G1 (G indicating gap), S (Synthesis), G2 (Gap 2), and M (Mitosis), and one outside, G0 (Gap 0).

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BMC Medical Genomics

ISSN: 1755-8794

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