|
No.
|
Protein
|
PDB
|
Score
|
Features
|
Spatial Features
|
R
|
H
|
D
|
A
|
N
|
P
|
Chemicals
|
Fig
|
|---|
|
1
|
BRCA1
|
4IFI
|
39.2
|
7
|
7
|
4
|
0
|
0
|
2
|
0
|
1
|
3
|
9-1
|
|
2
|
CDK2
|
3QQK
|
33.1
|
5
|
5
|
4
|
0
|
0
|
1
|
0
|
0
|
3
|
9-2
|
|
3
|
CEBPB
|
2E42
|
40.4
|
12
|
12
|
3
|
5
|
0
|
4
|
0
|
0
|
3
|
9-3
|
|
4
|
CREBBP
|
4A9K
|
29.9
|
5
|
5
|
1
|
0
|
2
|
2
|
0
|
0
|
9
|
9-4
|
|
5
|
CTNNB1
|
3TX7
|
23.7
|
3
|
3
|
2
|
0
|
0
|
1
|
0
|
0
|
7
|
9-5
|
|
6
|
CUL1
|
4F52
|
37.5
|
7
|
7
|
4
|
1
|
0
|
2
|
0
|
0
|
3
|
9-6
|
|
7
|
CUL3
|
4EOZ
|
25.7
|
5
|
5
|
2
|
0
|
0
|
3
|
0
|
0
|
3
|
9-7
|
|
8
|
EP300
|
4BHW
|
3.0
|
2
|
2
|
0
|
0
|
0
|
2
|
0
|
0
|
2
|
9-8
|
|
9
|
ESR1
|
1UOM
|
33.1
|
5
|
5
|
4
|
0
|
0
|
1
|
0
|
0
|
3
|
9-9
|
|
10
|
HDAC1
|
4BKX
|
26.5
|
4
|
4
|
3
|
0
|
0
|
0
|
0
|
1
|
4
|
9-10
|
|
11
|
HDAC2
|
4LY1
|
6.0
|
3
|
3
|
1
|
0
|
0
|
2
|
0
|
0
|
2
|
9-11
|
|
12
|
HDAC4
|
2VQM
|
34.0
|
7
|
5
|
0
|
0
|
2
|
5
|
0
|
0
|
3
|
9-12
|
|
13
|
IRAK4
|
2NRU
|
44.5
|
13
|
11
|
2
|
1
|
3
|
6
|
0
|
1
|
3
|
9-13
|
|
14
|
ISG15
|
3SDL
|
42.7
|
16
|
14
|
3
|
7
|
2
|
3
|
0
|
1
|
3
|
9-14
|
|
15
|
KIAA0101
| |
26.5
|
4
|
4
|
2
|
0
|
1
|
1
|
0
|
0
|
3
|
9-15
|
|
16
|
MDM2
|
4MDN
|
36.0
|
5
|
5
|
3
|
0
|
0
|
2
|
0
|
0
|
6
|
9-16
|
|
17
|
MYC
|
1NKP
| | | | | | | | | | |
9-17
|
|
18
|
PCNA
|
3WGW
|
36.0
|
14
|
14
|
3
|
9
|
0
|
2
|
0
|
0
|
3
|
9-18
|
|
19
|
PRKDC
|
3KGV
|
36.7
|
7
|
7
|
3
|
0
|
3
|
1
|
0
|
0
|
3
|
9-19
|
|
20
|
PSMA3
| |
14.7
|
3
|
3
|
1
|
0
|
0
|
2
|
0
|
0
|
3
|
9-20
|
|
21
|
RB1
|
3POM
|
36.4
|
4
|
4
|
3
|
0
|
0
|
1
|
0
|
0
|
9
|
9-21
|
|
22
|
SRC
|
2SRC
|
35.7
|
6
|
6
|
3
|
0
|
0
|
3
|
0
|
0
|
4
|
9-22
|
|
23
|
TERF1
|
3BQO
|
36.5
|
7
|
7
|
3
|
1
|
0
|
3
|
0
|
0
|
4
|
9-23
|
|
24
|
TP53
|
1TSR
|
33.8
|
6
|
6
|
4
|
1
|
1
|
0
|
0
|
0
|
3
|
9-24
|
|
25
|
TRAF2
|
1D0A
|
30.9
|
3
|
3
|
2
|
0
|
0
|
1
|
0
|
0
|
16
|
9-25
|
|
26
|
UBC
|
4FJV
|
41.6
|
10
|
9
|
3
|
1
|
1
|
5
|
0
|
0
|
3
|
9-26
|
|
27
|
XRCC6
|
1JEQ
|
141.1
|
22
|
22
|
0
|
0
|
10
|
12
|
0
|
0
|
3
|
9-27
|
|
28
|
YWHAZ
|
4HKC
|
34.9
|
3
|
3
|
3
|
0
|
0
|
0
|
0
|
0
|
12
|
9-28
|
- Their pharmacophore diagrams are shown in Figure 7.
