Skip to main content
Figure 4 | BMC Medical Genomics

Figure 4

From: g-FLUA2H: a web-based application to study the dynamics of animal-to-human mutation transmission for influenza viruses

Figure 4

g-FLUA2H output for a representative PB2 nonamer position containing the E627K substitution, reported to be crucial for host tropism. The representative position for H5N1 (panel A) and H7N9 (panel B) are the same, 623-631. The output provides detailed information on the distinct nonamer sequences reported at the position for both animal and human hosts of the virus, such as their motif classifications and incidences (% occurrence), amino acid substitutions relative to the index, strain name of origin virus in animal and human hosts, host species of the animal host, and the geographical distribution of the human host. The dropdown menu for each of the distinct nonamer sequences shows the animal species origin, strain names of origin virus in animal and human hosts, and geographical locations of the viral isolate for the human host. The pie-charts show the frequency distribution of the animal host species origin and the geographical location of the human isolates for the nonamer position as a whole, covering all the distinct sequences.

Back to article page