From: A common gene expression signature in Huntington’s disease patient brain regions
Module | cor | GO-term (DAVID) | Transcription factor |
---|---|---|---|
Hdh Q150 | |||
Q150pos1 | up | extracellular matrix (1.71, 0.65) | |
Q150neg1 | down | synaptic transmission/synapse (8.81, 0.000) | CREB (0.045)1 |
neuron projection/axon (2.4, 0.019) | |||
mitochondrion (2.1, 0.007) | |||
R6/2 | |||
R6/2pos1 | up | fatty acid metabolism (1.98, 0.13) | SOX9 (0.049)2 |
R6/2neg1 | down | synaptic transmission (6.77, 0.000) | |
gated channel activity (2.3, 0.02) | |||
neurotransmitter transport (2.08, 0.005) | |||
R6/2neg2 | down | ion transport (1.68, 0.64) |