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Table 4 Association between BRAF detection rate and QFI status for PTC samples

From: Evaluation of an integrated clinical workflow for targeted next-generation sequencing of low-quality tumor DNA using a 51-gene enrichment panel

All PTC samples, N = 30

 

Luminex

1052-amplicon

 

BRAF WT

BRAF mutant

BRAF WT

BRAF mutant

QFI = 0%

9

1

10

0

0% < QFI < = 3%

6

7

8

5

QFI > 3%

2

5

2

5

Fisher-test p-value

0.03

0.005

  1. When considering the 30 PTC sample subset of the 72 sample Thyroid set, both the Luminex and the 1052-amplicon panel showed a significant association between BRAF detection and QFI status.
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BMC Medical Genomics

ISSN: 1755-8794

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