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Table 4 Genomic segments significantly over- or under-expressed

From: Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)

a) DS AMKL vs. normal CB MK
Chr and location a Segment start b Segment end b 'A'/'E' ratio q-value Genes in the segment c
Over-expressed segments      
chr3 3q22.1 130,000,001 130,500,000 80.36 0.00015 COL6A5 + COL6A6 + Hs.596709+ Hs.596805+ PIK3R4-
Under-expressed segments
chr7 7q11.23 77,000,001 77,500,000 0.48 0.00117 GSAP - PTPN12 - LOC101059910- RSBN1L-AS1- RSBN1L- Hs.594486- Hs.720279- TMEM60- PHTF2-
chr4 4q12-q21 74,750,001 75,250,000 0.37 0.00119 PF4 - PPBP - CXCL5- CXCL3 - CXCL2- MTHFD2L- Hs.662627- EREG-
chr4 4q32.1 156,250,001 156,750,000 0.12 0.00000 MAP9 - GUCY1A3 - Hs.612374 - GUCY1B3 -
b) Non-DS AMKL vs. normal CB MK
Chr and location Segment start Segment end 'B'/'E' ratio q-value Genes in the segment
Over-expressed segments
chr3 3q22.1 130,000,001 130,500,000 116.13 0.00030 COL6A5 + COL6A6 + Hs.596709+ Hs.596805+ PIK3R4-
chr11 11p15 6,750,001 7,250,000 50.98 0.00117 OR6A2+ OR10A5 + OR10A4 + ZNF215- ZNF214- Hs.445849+ NLRP14+ RBMXL2- LOC100506238+
Under-expressed segments
chr4 4q12-q21 74,750,001 75,250,000 0.42 0.00003 PF4 - PPBP - CXCL5 - CXCL3 - CXCL2- MTHFD2L- Hs.662627- EREG-