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Figure 2 | BMC Medical Genomics

Figure 2

From: Transcriptome profiling and pathway analysis of genes expressed differentially in participants with or without a positive response to topiramate treatment for methamphetamine addiction

Figure 2

Integrated model of the biological pathways related to TPM treatment for methamphetamine addiction. The joint effects of TPM and methamphetamine act on multiple molecular pathways that eventually result in modulations of neuroplasticity and neurotoxicity/neurodegeneration, which have a combined effect on cognitive/behavioral function. Pathways enriched exclusively in the TPM responder groups at Weeks 8 and 12 are highlighted in gray.

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BMC Medical Genomics

ISSN: 1755-8794

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