From: “Genotype-first” approaches on a curious case of idiopathic progressive cognitive decline
p.Y309C | p.R565W | |
---|---|---|
SIFT score | 0 | 0 |
SIFT prediction | Deleterious | Deleterious |
PolyPhen score | 1 | 1 |
PolyPhen prediction | Probably damaging | Probably damaging |
LRT score | 0 | 0 |
LRT prediction | Neutral | Deleterious |
Mutation Taster score | 1 | 1 |
Mutation Taster prediction | Disease causing | Disease causing automatic |
Mutation Assessor score | 3.55 | 3.46 |
Mutation Assessor prediction | High | Medium |
FATHMM score | −6.27 | −5.82 |
FATHMM prediction | Deleterious | Deleterious |
MetaSVM score | 1.05 | 1.05 |
MetaSVM prediction | Deleterious | Deleterious |
MetaLR score | 0.99 | 0.98 |
MetaLR prediction | Deleterious | Deleterious |
Tute score | 0.92 | 0.92 |
Tute prediction | Deleterious | Deleterious |