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Figure 2 | BMC Medical Genomics

Figure 2

From: High throughput exome coverage of clinically relevant cardiac genes

Figure 2

Cumulative coverage with Agilent capture kit versions. Graph showing proportion of CCDS and Known Gene datasets covered at various read depths by four Agilent capture kit versions. Coverage of CCDS coordinates is shown in blue while coverage of Known Gene coordinates is depicted in red. There was good coverage, 92-99% of CCDS target regions, at a minimum read depth of 3X but only 55-64% coverage of Known Gene target regions at 3X. A. Proportion of CCDS and Known Gene read depths for the Agilent 44MB_V2 capture kit. B. Proportion of CCDS and Known Gene read depths for the Agilent 50MB_V3 kit. This capture kit version demonstrated the highest overall observed read depth. C. Proportion of CCDS and Known Gene read depths for the Agilent 51MB_V4 kit. D. Proportion of CCDS and Known Gene read depths for the Agilent 50MB_V5 kit.

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