Table 1 Differentially expressed proteins in different subtypes of clinically nonfunctional pituitary adenomas versus controls

1011

Chain 1: somatotropin

P01241

180.6(−)

44.1(−)

82.6(−)

90.5(−)

1017

Chain 1: somatotropin

P01241

13.3(−)

1017

Splice isoform 2 of somatotropin precursor

P01241 isoform

13.3(−)

1102

Chain 1: somatotropin

P01241

20.2(−)

6.5(−)

9.1(−)

9.3(−)

1103

Somatotropin precursor

P01241

14.1(−)

2.9(−)

3.3(−)

5.8(−)

1103

Growth hormone variant precursor

P01242

14.1(−)

2.9(−)

3.3(−)

5.8(−)

1109

Chain 1: somatotropin

P01241 isoform

(−−)

128.3(−)

69.4(−)

(−−)

1121

Chain 1: somatotropin

P01241

6.2(−)

2.8(−)

2.7(−)

3.3(−)

1122

Chain 1: somatotropin

P01241

48.1(−)

(−−)

7.5(−)

8.1(−)

1123

Chain 1: somatotropin

P01241

17.3(−)

4.4(−)

6.4(−)

(−−)

2002

Splice isoform 2 of somatotropin precursor

P01241 isoform

9.7(−)

3.9(−)

3.2(−)

5.4(−)

2003

Chain 1: somatotropin

P01241

(−−)

88.8(−)

25.0(−)

(−−)

2101

Chain 1: somatotropin

P01241

27.8(−)

(−−)

17.4(−)

2106

Chain 1: somatotropin

P01241

(−−)

9.4(−)

2.2(−)

51.2(−)

2115

Chain 1: somatotropin

P01241

(−−)

32.1(−)

(−−)

(−−)

2128

Chain 1: somatotropin

P01241

(−−)

82.1(−)

67.4(−)

478.6(−)

2129

Chain 1: somatotropin

P01241

13.4(−)

6.7(−)

4.3(−)

5.5(−)

3004

Chain 1: somatotropin

P01241

42.0(−)

37.0(−)

21.2(−)

13.6(−)

3107

Chain 1: somatotropin

P01241

30.5(−)

(−−)

19.1(−)

34.9(−)

4106

Chain 1: prolactin

P01236

8.3(−)

12.6(−)

46.2(−)

99.9(−)

4215

Prolactin precursor

P01236

4.9(−)

4.1(−)

3.8(−)

4216

Chain 1: prolactin

P01236

26.2(−)

14.6(−)

12.3(−)

5114

Chain 1: prolactin

P01236

(−−)

20.1(−)

17.6(−)

19.0(−)

6109

Chain 1: prolactin

P01236

(−−)

36.7(−)

(−−)

19.7(−)

6119

Chain 1: prolactin

P01236

(−−)

33.6(−)

11.3(−)

32.6(−)

0020

Splice isoform IL15-S21AA of interleukin-15 precursor

P40933-2 isoform

(−−)

(−−)

1.6(−)

2.7(−)

0029

Chain 1: Factor X light chain

P00742

(−−)

(−−)

29.3(−)

38.9(−)

0511

Cytokeratin 16

P08779

28.8(−)

2.1(−)

15.7(−)

18.5(−)

0112

Alpha crystallin C chain

Q9UJY1

(−−)

2.3(−)

(−−)

(−−)

0812

Chain 1: Endoplasmin (Tumor rejection antigen 1)

P14625

11.0(−)

4.4(−)

1010

14-3-3 protein tau

P27348

(−−)

(−−)

6.4(−)

15.5(−)

1012

Splice isoform 3 of alpha-s1 casein precursor

P47710-3 isoform

17.8(−)

1117

Chain 1: apolipoprotein A-I

P02647

2.1(−)

1311

Secretagogin

O76038

6.6(−)

2.1(−)

2.3(−)

3.4(−)

1402

Mu-crystallin homolog

Q14894

16.3(−)

4.6(−)

2.4(−)

4.6(−)

1404

Chain 1: MIMECAN

P20774

38.0(−)

6.1(−)

9.1(−)

16.2(−)

1806

Tissue transglutaminase

P21980

(−−)

17.1(−)

(−−)

(−−)

2001

CD59 glycoprotein

P13987

9.5(−)

2.4(−)

4.1(−)

2303

Serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, alpha isoform

Q00007

8.2(−)

2.6(−)

2311

L-Myc-1 protooncogene protein

P12524

7.4(−)

2624

Chain 1: dipeptidyl-peptidase II

Q9UHL4

9.3(−)

2.5(−)

5.3(−)

3210

Heat shock protein 27

P04792

2.4(−)

4.9(−)

4001

ATP binding protein associated with cell differentiation

O14530

11.4(−)

2.3(−)

2.7(−)

4.4(−)

4921

Chain 1: collagen alpha 2 (VI) chain

P12110

5.3(−)

14.7(−)

5003

Hemoglobin beta-2 chain

P18988

3.1(−)

2.1(−)

6103

N6-adenosine-methyltransferase 70 kDa subunit

Q86U44

6.2(−)

6.5(−)

(−−)

8.3(−)

7004

Hemoglobin beta unit variant

gi1066765

(−−)

176.7(−)

(−−)

(−−)

7014

Hemoglobin beta-2 chain

P18988

(−−)

29.4(−)

28.9(−)

99.4(−)

7016

Hemoglobin alpha-2 chain

P01968

20.2(−)

13.3(−)

8101

Chain 1: insulin-like growth factor binding

P24592

(−−)

2.9(−)

20.9(−)

5.0(−)

8102

Chain 1: phospholipid hydroperoxide glutathione peroxidase

P36969

3.9(−)

2.1(−)

14.4(−)

8208

Ig kappa chain V-III region SIE

P01620

4.1(−)

32.5(−)

0118

Lactoylglutathione lyase

Q04760

9.1(+)

10.2(+)

1105

Lactoylglutathione lyase

Q04760

6.6(+)

8.3(+)

5.1(+)

1107

NADH-ubiquinone oxidoreductase 23 kDa

O00217

4.9(+)

5.2(+)

1608

ATP synthase beta chain, mitochondrial precursor

P06576

5.0(+)

3.1(+)

2.8(+)

1610

Vimentin

P08670

5.5(+)

2.6(+)

1705

Rab GDP dissociation inhibitor alpha

P31150

9.4(+)

5.8(+)

2008

Enhancer of rudimentary homolog

Q14259

5.0(+)

3.7(+)

2310

F-actin capping protein beta subunit

P47756

2.7(+)

2.2(+)

6.5(+)

3.0(+)

2310

Splice isoform 2 of F-actin capping protein beta subunit

P47756-2 isoform

2.7(+)

2.2(+)

6.5(+)

3.0(+)

2416

Zinc finger protein 266

Q14584

3.4(+)

2.4(+)

7.3(+)

2.8(+)

2419

Guanine nucleoide-binding protein G(O), alpha subunit 1

P09471

7.3(+)

2.1(+)

9.1(+)

9.5(+)

2419

Guanine nucleotide-binding protein G(O), alpha subunit 2

P29777

7.3(+)

2.1(+)

9.1(+)

9.5(+)

3013

Acyl-CoA-binding protein

P07108

2.7(+)

4.3(+)

3222

Chain 1: Endoplasmic reticulum protein ERP29

P30040

4.1(+)

4012

Cytochrome c oxidase polypeptide VIb

P14854

4.4(+)

8.7(+)

4313

Aldose reductase

P15121

5.7(+)

9.6(+)

14.6(+)

8.1(+)

4616

Tryptophan 5-hydroxylase (Neuronal tryptophan hydroxylase)

Q8IWU9

10.6(+)

2.1(+)

7.8(+)

8.3(+)

5207

Glutathione S-transferase Mu-2

P28161

2.5(+)

2.8(+)

4.2(+)

2.9(+)

5617

Proto-oncogene tyrosine-protein kinase FYN

P06241

2.8(+)

3.9(+)

6115

Neuronal protein NP25

Q9UI15

4.9(+)

4.6(+)

6508

Isocitrate dehydrogenase [NADP] cytoplasmic

O75874

6.1(+)

6.7(+)

8.7(+)

4.4(+)

7503

Peroxisomal acyl-coenzyme A thioester hydrolase 2a

P49753

2.8(+)

2.0(+)

2.2(+)

2.5(+)

7519

Chain 1: matrix metalloproteinase-19

Q99542

3.1(+)

7106

40 kDa peptidyl-prolyl cis-trans isomerase

Q08752

4.3(+)

5.0(+)

5.1(+)