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Table 3 Top eight pathway analysis results for white module (unique gene symbols n = 32)

From: Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods

GO category

ID

Genes in category

p-value

FDR q-value

B cell receptor signaling pathway

GO:0050853

2

0.00072

0.10

Antigen processing and presentation of exogenous peptide antigen via MHC class II

GO:0019886

2

0.0055

0.13

Antigen receptor-mediated signaling pathway

GO:0050851

2

0.011

0.13

Skeletal muscle tissue development

GO:0007519

2

0.029

0.18

Skeletal muscle organ development

GO:0060538

2

0.031

0.18

Clustering of voltage-gated potassium channels

GO:0045163

1

0.0036

0.13

Protein localization to juxtaparanode region of axon

GO:0071205

1

0.0048

0.13

Positive regulation of humoral immune response mediated by circulating immunoglobulin

GO:0002925

1

0.0073

0.13

KEGG category

ID

Genes in category

p-value

FDR q-value

B cell receptor signaling pathway

04662

4

7.6E-006

0.00018

Cell adhesion molecules (CAMs)

04514

4

7.4E-005

0.00088

Asthma

05310

2

1.4E-003

0.011

Allograft rejection

05330

2

2.1E-003

0.011

Graft-versus-host disease

05332

2

2.5E-003

0.011

Type I diabetes mellitus

04940

2

2.8E-003

0.011

Intestinal immune network for IgA production

04672

2

3.4E-003

0.012

Autoimmune thyroid disease

05320

2

4.0E-003

0.012