Meta-analysis of prostate cancer gene expression data identifies a novel discriminatory signature enriched for glycosylating enzymes

Table 6 71-gene signature capable of subclustering localised prostate cancer cases across multiple datasets

Category	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
KEGG_PATHWAY	hsa00512:O-Glycan biosynthesis	3	0.34	0.01	GALNTL4, GCNT1, ST6GALNAC1	26	30	5085	19.56	0.43	0.43	8.95
KEGG_PATHWAY	hsa04610:Complement and coagulation cascades	3	0.34	0.04	C4A, C4B, SERPINA1	26	69	5085	8.5	0.94	0.75	36.76
KEGG_PATHWAY	hsa05322:Systemic lupus erythematosus	3	0.34	0.08	C4A, C4B, HLA-DMB	26	99	5085	5.93	1	0.83	58.75

Genes were uploaded into the DAVID gene ontology search engine (http://david.abcc.ncifcrf.gov/). KEGG pathway enrichment was generated and the table represents the output file ranked based on significance and annotated by column header.

ISSN: 1755-8794