Figure 1

MiRNA targeted signaling pathways in four different important cells including plaque macrophage, platelet, monocyte and endothelial cell. Bioinformatic analysis was used to find significantly upregulated miRNAs target genes. Those target genes were clustered based on SAGE genie and categorized into four cell types. Each cell specific genes were then functionally clustered according to Reactome pathway. The two steps were performed in DAVID functional clustering tools and the figure was generated using CytoScape. The pathway which was targeted by only one miRNA was not displayed.