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Figure 6 | BMC Medical Genomics

Figure 6

From: Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy

Figure 6

Hypothetical model of the transcriptional regulatory network in ICM patients. Expression of the TFs, CITED2, CEBPD and BCL3, and SP100 is downregulated under conditions of hypoxia and other stress stimuli, which in turn modifies the expression of their target gene networks. These changes ultimately result in alterations in cellular processes that are characteristic of ICM.

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BMC Medical Genomics

ISSN: 1755-8794

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