Table 3 Identification and functional annotation analysis of TF target genes
FT | GO | p-value | Genes |
|---|---|---|---|
CEBPD | System development | 5.00E-05 | CITED2, RGMA, BMPR1B, CALCRL, FGF7, IL1B, IRX3, LRRC4C, RXFP2, TGFBR2, TNFRSF11A |
CEBPD | Negative regulation of apoptosis | 1.10E-02 | CITED2, RIPK2, IL1B, RXFP2 |
CEBPD | Negative regulation of programmed cell death | 1.20E-02 | CITED2, RIPK2, IL1B, RXFP2 |
CEBPD | Blood vessel morphogenesis | 3.20E-02 | CTH, IL1B, RXFP2, TGFBR2 |
CEBPD | Negative regulation of cell proliferation | 1.20E-02 | CITED2, TGFBR2, IL1B |
BCL3 | Regulation of metabolic process | 4.80E-04 | PFKFB2, ABCA1, ATPIF1, FOSL2, GABPB2, SP110, TSPYL2, ATF7, A2M, ANKRD1, CALCRL, GDF7, HR, MLYCD, MYD88, NR4A1, NR4A3, PER1, PIM1, PDCD4, PSMB9, STAT2, SOAT1, TXNIP, TGFBR2, TGFBR3, UBB, UBE2L6, ETS2 |
BCL3 | Regulation of nitrogen compound metabolic process | 6.30E-03 | ABCA1, ATPIF1, FOSL2, GABPB2, SP110, TSPYL2, ATF7, ANKRD1, CALCRL, GDF7, HR, MYD88, NR4A1, NR4A3, PER1, PIM1, PDCD4, STAT2, TXNIP, TGFBR3, UBB, ETS2 |
BCL3 | Response to glucose stimulus | 1.60E-02 | PFKFB2, TXNIP, TGFBR2 |
BLC3 | Response to hexose stimulus | 1.80E-02 | PFKFB2, TXNIP, TGFBR2 |
BCL3 | Response to monosaccharide stimulus | 1.80E-02 | PFKFB2, TXNIP, TGFBR2 |
CITED2/HIF1A | Response to hypoxia | 9.80E-06 | ANGPTL4, EGLN3, NOL3, KCNA5 |
CITED2/HIF1A | Response to oxygen levels | 1.20E-05 | ANGPTL4, EGLN3, NOL3, KCNA5 |
CITED2/HIF1A | Response to stress | 9.20E-04 | ANGPTL4, CCND1, EGLN3, MIF, NOL3, KCNA5, TFF3 |
CITED2/HIF1A | Regulation of cell proliferation | 8.00E-03 | CCND1, DPT, EGLN3, ADM, IGFBP3 |