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Table 1 HS gene list

From: Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxin

p value

FC

GeneSymbol

Description

Genbank Acc

3.36E-04

1.56

ATHL1

Acid trehalase-like 1

NM_025092

5.53E-03

-1.61

APCDD1

Adenomatosis polyposis coli down-regulated 1

NM_153000

2.02E-04

1.63

AEBP1

AE binding protein 1

NM_001129

1.47E-03

1.52

ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

NM_000927

2.91E-05

1.62

CELSR3

Cadherin, EGF LAG seven-pass G-type receptor 3

NM_001407

1.34E-03

1.62

CD274

CD274 molecule (CD274), transcript variant 1

NM_014143

7.44E-05

-1.56

CD36

CD36 molecule (thrombospondin receptor)

NM_001001547

4.01E-04

-1.90

CD9

CD9 molecule

NM_001769

9.33E-05

1.51

LOC100289090

cDNA FLJ33063 fis, clone TRACH2000047

AK057625

3.24E-04

1.60

LOC692247

cDNA FLJ36520 fis, clone TRACH2002100

AK093839

4.36E-03

1.51

C17orf66

Chromosome 17 open reading frame 66

NM_152781

4.00E-06

1.81

C6orf163

Chromosome 6 open reading frame 163

NM_001010868

7.42E-04

-1.68

CYB5R2

Cytochrome b5 reductase 2

NM_016229

1.33E-03

2.16

DDX43

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

NM_018665

7.91E-03

1.76

EIF4G3

Eukaryotic translation initiation factor 4 gamma 3

NC_018912.2

3.33E-07

1.51

N/A

Formin-like 1 protein (Leukocyte formin)

AC_000149.1

4.71E-04

1.67

GPR125

G protein-coupled receptor 125

NM_145290

8.75E-03

1.79

GATA2

GATA binding protein 2 (GATA2), transcript variant 1

NM_001145661

5.97E-03

1.54

GZMK

Granzyme K (granzyme 3; tryptase II)

NM_002104

3.89E-04

1.51

GBP5

Guanylate binding protein 5 variant 1

NM_052942

1.74E-03

1.53

LRRC37A4P

Hypothetical protein LOC652203

BC107850

1.01E-03

-3.85

ITGB2

Integrin beta chain, beta 2 variant (Fragment)

NC_018932.2

5.33E-03

-1.69

IL5RA

Interleukin 5 receptor, alpha, variant 3

NM_175725

1.75E-03

1.66

NEAT1

lncRNA Nuclear paraspeckle assembly transcript 1

AF001893

6.55E-04

1.55

LINC00282

lncRNA 282 (LINC00282)

NR_027047

1.08E-04

1.58

HYMAI

lncRNA Hydatidiform mole associated and imprinted

NR_002768

3.66E-04

1.74

LMF1

lncRNA Lipase maturation factor 1 variant 4

NR_036442

3.62E-05

-1.89

N/A

lncRNA TCONS_l2_00011463

NC_018928

4.20E-03

-1.73

LYPD2

LY6/PLAUR domain containing 2

NM_205545

4.37E-03

-1.63

MARCO

Macrophage receptor with collagenous structure

NM_006770

1.85E-03

-2.43

N/A

Major histocompatibility complex, class I, V (pseudogene)

NC_018917

2.95E-03

-1.61

HLA-DQB1

MHC class II, DQ beta 1 variant 1

NM_002123

6.20E-03

-2.16

HLA-DQB1

MHC class II, DQ beta 1 variant 2

NM_001243961

8.09E-04

-1.54

HLA-DQB1

MHC class II, DQ beta 1 variant 3

NM_001243962

2.96E-04

-2.13

PADI6

Peptidyl arginine deiminase, type VI

NM_207421

4.12E-05

-2.26

PEX6

Peroxisomal biogenesis factor 6

NM_000287

3.69E-04

-1.82

PEX6

Peroxisomal biogenesis factor 6

NM_000287

9.37E-03

1.55

PDE4DIP

Phosphodiesterase 4D interacting protein variant 1

NM_014644

3.56E-03

1.80

PLGLB1

Plasminogen-like B1

BC022294

2.19E-03

1.51

LOC345051

Predicted: hCG38984 variant X1

XR_109844

3.22E-03

-1.74

PPP1R17

Protein phosphatase 1, regulatory subunit 17 variant 1

NM_006658

8.37E-03

-1.67

PDK4

Pyruvate dehydrogenase kinase, isozyme 4

NM_002612

2.41E-04

-1.51

ARHGAP22

Rho GTPase activating protein 22, variant 3

NM_021226

8.34E-04

1.52

ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

AK090448

6.37E-03

7.57

SIGLEC14

Sialic acid binding Ig-like lectin 14

NM_001098612

8.88E-06

1.55

SIGIRR

Single immunoglobulin and toll-interleukin 1 receptor

XM_005253044

1.58E-04

1.53

TCRBV27

T cell receptor beta variable 27

AB305921

1.22E-03

2.02

TCRBV28

T cell receptor beta variable 28

AY751906

1.55E-03

2.34

TCRBV28

T cell receptor beta variable 28

AB305916

3.33E-04

1.51

TCRBV6

T cell receptor beta variable 6-4

A25966

6.60E-03

-1.77

TOLLIP

Toll interacting protein

NM_019009

3.79E-03

3.03

TUBB2A

Tubulin, beta 2A class Iia

NM_001069

1.36E-03

1.55

VIPR2

Vasoactive intestinal peptide receptor 2

NM_003382

3.82E-03

-1.71

VWF

von Willebrand factor

NM_000552

8.82E-03

2.74

ZFP57

ZFP57 zinc finger protein

NM_001109809

  1. Genes that exhibited a FC > 1.5 and p < 0.01 in patients v controls. Bold shading indicates PCR analysis, italics indicates genes with the highest loading factors in PCA analysis. Genes sorted by description.