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Table 4 Pathogenic indels in BIC, ClinVar, or SIFT indel prediction

From: New recurrent BRCA1/2 mutations in Polish patients with familial breast/ovarian cancer detected by next generation sequencing

Variant rs Type BIC ClinVar SIFT Count
  BRCA1
c.4516delG rs273900736 F pathogenic   not-tested 4
c.5137delG rs80357997 F pathogenic pathogenic not-tested 1
c.1695insG rs273897664 F pathogenic   not-tested 1
c.340delTC rs80357881 F pathogenic   not-tested 1
c.5285insG rs80357886 F pathogenic   not-tested 1
c.4597delGA   F   pathogenic 1
c.5232del7ins12   F   pathogenic 1
c.403delA   F   pathogenic 1
c.403delAAGA   F   pathogenic 1
  BRCA2
c.7249delCA   F   pathogenic 3
c.475 + 4delT rs276174848 IVS unknown likely pathogenic not-tested 1
c.696delT rs80359630 F pathogenic   not-tested 1
c.2808delACAA rs80359352 F pathogenic   not-tested 1
c.1318delCTTA   F   pathogenic 1
c.8840delA   F   pathogenic 1
c.8942delA   F   pathogenic 1
c.9375delC   F   pathogenic 1
  1. IVS intronic variant near splice site, F frameshift variant.