TY - JOUR AU - Castellani, Christina A. AU - Laufer, Benjamin I. AU - Melka, Melkaye G. AU - Diehl, Eric J. AU - O’Reilly, Richard L. AU - Singh, Shiva M. PY - 2015 DA - 2015/05/06 TI - DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks JO - BMC Medical Genomics SP - 17 VL - 8 IS - 1 AB - Despite their singular origin, monozygotic twin pairs often display discordance for complex disorders including schizophrenia. It is a common (1%) and often familial disease with a discordance rate of ~50% in monozygotic twins. This high discordance is often explained by the role of yet unknown environmental, random, and epigenetic factors. The involvement of DNA methylation in this disease appears logical, but remains to be established. SN - 1755-8794 UR - https://doi.org/10.1186/s12920-015-0093-1 DO - 10.1186/s12920-015-0093-1 ID - Castellani2015 ER -