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Table 5 Gene set enrichment testing of KEGG pathway for nominally significant transcripts in Beta(0.5,0.5) and Beta(1,1) (p-value < 0.1)

From: The cis and trans effects of the risk variants of coronary artery disease in the Chr9p21 region

 

Term

Number of genes

P value

Enriched transcript

Beta(0.5,0.5)

hsa00830:Retinol metabolism

5

0.016

ENST00000394887, ENST00000001146, ENST00000432060, ENST00000412271, ENST00000336356

 

hsa04350:TGF-beta signaling pathway

4

0.056

ENST00000416274, ENST00000224764, ENST00000394092, ENST00000401753

 

hsa00510:N-Glycan biosynthesis

3

0.077

ENST00000393487, ENST00000413355, ENST00000250498

Beta(1,1)

hsa00830:Retinol metabolism

6

0.002

ENST00000335125, ENST00000394887, ENST00000001146, ENST00000432060, ENST00000412271, ENST00000336356

 

hsa04350:TGF-beta signaling pathway

4

0.056

ENST00000416274, ENST00000224764, ENST00000394092, ENST00000401753