Table 2 Gene ontology analysis of genes expressed at higher and lower levels in T2DM vs MetS
GO analysis of genes expressed at higher levels in T2DM vs MetS: | |||
|---|---|---|---|
Biological process | nr in genome | nr sign genes | p-value |
Metabolic process | 8,127 | 183 | 5.13E-04 |
Primary metabolic process | 7,813 | 175 | 1.06E-03 |
Protein transport | 1,542 | 44 | 3.29E-03 |
Intracellular protein transport | 1,542 | 44 | 3.29E-03 |
Cell cycle | 1,602 | 45 | 3.94E-03 |
GO analysis of genes expressed at lower levels in T2DM vs MetS: | |||
Metabolic process | 8,127 | 113 | 1.15E-06 |
Primary metabolic process | 7,813 | 109 | 2.04E-06 |
Translation | 453 | 14 | 1.75E-04 |
Organelle organization | 295 | 11 | 1.83E-04 |
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 3,782 | 58 | 2.04E-04 |
Establishment or maintenance of chromatin architecture | 269 | 10 | 3.68E-04 |
Protein metabolic process | 3,178 | 49 | 6.75E-04 |
Transcription from RNA polymerase II promoter | 2,214 | 37 | 8.63E-04 |
RNA metabolic process | 663 | 16 | 9.19E-04 |
Transcription | 2,224 | 37 | 9.36E-04 |
Cell cycle | 1,602 | 29 | 1.02E-03 |
Nuclear mRNA splicing, via spliceosome | 371 | 11 | 1.21E-03 |
Cellular component organization | 1,255 | 24 | 1.39E-03 |
mRNA processing | 456 | 12 | 1.98E-03 |
Hemopoiesis | 183 | 6 | 9.83E-03 |