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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model

Fig. 2

Enrichment analysis of biologically modulated pathways. Analysis first shows a significant enrichment in TGFbeta signaling modulated by SMAD proteins: as the majority of genes are down-regulated, we have inhibition of this pathway in Saos clones, with an effect that increases over time. Other important and significantly modulated are the EMT and Apoptotic pathways. (min (p-value) = most significant p-value among the 3 time points after multiple correction test)

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BMC Medical Genomics

ISSN: 1755-8794

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