Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model

BMC Medical Genomics

Table 2 Significantly modulated miRNAs in Sa/CD99 vs Saos-2 cells. For each day, log fold change and significance are shown

microRNA	Genomic position	Log fold change			Significance
microRNA	Genomic position	Day 0	Day 7	Day 14	Day 0	Day 7	Day 14
hsa-miR-378	Ch5q32	−0.938	−0.323	0.109	0.00015	ns	ns
hsa-miR-34a	Ch1p36	0.777	0.781	0.327	0.00177	0.00171	ns
hsa-miR-1225-3p	Ch16p13	1.206	0.142	0.050	0.00193	ns	ns
hsa-miR-1305	Ch4q34	0.757	−0.965	1.750	0.00466	0.00108	0.00001
hsa-miR-1238	Ch19p13	0.969	0.627	−0.302	0.00593	ns	ns
hsa-miR-425*	Ch3p21	0.910	0.537	−0.199	000841	ns	ns
hsa-miR-191*	Ch3p21	1.027	0.553	−0.216	0.00859	ns	ns
hsa-miR-892b	ChXq27	0.176	−1.047	0.999	ns	0.00006	0.00008
hsa-miR-139-3p	Ch11q13	0.024	−1.562	1.013	ns	0.00017	0.00289
hsa-miR-500	ChXp11	0.008	−0.249	0.818	ns	ns	0.00066
hsa-miR-760	Ch1p22	−0.058	−0.251	0.737	ns	ns	0.00199
hsa-miR-1299	Ch9q21	−0.040	−0.260	0.778	ns	ns	0.00234
hsa-miR-342-3p	Ch14q32	−0.834	−0.808	−1.018	ns	ns	0.00428
hsa-miR-1181	Ch19p13	0.045	0.385	0.672	ns	ns	0.00473
hsa-miR-516a-5p	Ch19q13	−0.001	−0.049	0.512	ns	ns	0.00529
hsa-miR-1288	Ch17p11	0.575	−0.866	1.269	ns	ns	0.00547
hsa-miR-150*	Ch19q13	0.177	0.113	0.784	ns	ns	0.00663
hsa-miR-1914*	Ch20q13	0.276	−0.230	1.040	ns	ns	0.00669
hsa-miR-26b	Ch2q35	−0.433	−0.443	−0.687	ns	ns	0.00809
hsa-miR-520e	Ch19q13	0.036	0.231	0.610	ns	ns	0.00809
hsa-miR-202	Ch10q26	0.007	−0.255	0.607	ns	ns	0.00882
hsa-miR-1469	Ch15q26	−0.032	−0.146	0.579	ns	ns	0.00892

ISSN: 1755-8794