Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model

Grilli, A.; Sciandra, M.; Terracciano, M.; Picci, P.; Scotlandi, K.

doi:10.1186/s12920-015-0106-0

BMC Medical Genomics

Table 3 Couples miRNA:gene after intersection of correlation and prediction approaches. There are 62 couples, where miR-34a shows the highest number of putative negatively correlated genes. When multiple probes per gene are significant, the most correlated is shown

From: Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model

		Correlation					Correlation
miR name	Gene symbol	Day 0	Day 7	Day 14	miR name	Gene symbol	Day 0	Day 7	Day 14
hsa-miR-1305	ID1	ns	ns	−0.886	hsa-miR-26b	ADAMTSL1	ns	ns	−0.929
hsa-miR-202	CBFA2T3	ns	ns	0.931	hsa-miR-26b	ADNP2	ns	ns	0.94
hsa-miR-34a	AKT3	ns	−0.909	ns	hsa-miR-26b	ARHGAP29	ns	ns	0.924
hsa-miR-34a	ARHGAP29	ns	−0.927	ns	hsa-miR-26b	C18orf25	ns	ns	0.918
hsa-miR-34a	C18orf25	−0.945	−0.917	ns	hsa-miR-26b	CDH2	ns	ns	0.968
hsa-miR-34a	C1orf74	0.827	0.827	ns	hsa-miR-26b	CNR1	ns	ns	0.844
hsa-miR-34a	CD40	0.945	ns	ns	hsa-miR-26b	DTNA	ns	ns	0.908
hsa-miR-34a	DOK6	−0.885	−0.885	ns	hsa-miR-26b	ELAVL2	ns	ns	0.885
hsa-miR-34a	DTNA	−0.892	ns	ns	hsa-miR-26b	HES1	ns	ns	0.909
hsa-miR-34a	GALM	ns	0.815	ns	hsa-miR-26b	HEY2	ns	ns	0.94
hsa-miR-34a	GRB10	ns	−0.842	ns	hsa-miR-26b	JAM2	ns	ns	0.9
hsa-miR-34a	KCTD12	ns	−0.87	ns	hsa-miR-26b	KIAA1468	ns	ns	0.917
hsa-miR-34a	KCTD21	ns	0.813	ns	hsa-miR-26b	MEX3C	ns	ns	0.99
hsa-miR-34a	LMAN1	−0.884	−0.88	ns	hsa-miR-26b	NEDD4L	ns	ns	0.883
hsa-miR-34a	MEX3C	−0.938	−0.938	ns	hsa-miR-26b	NTNG1	ns	ns	0.907
hsa-miR-34a	NTNG1	−0.856	−0.856	ns	hsa-miR-26b	PLEKHA7	ns	ns	0.863
hsa-miR-34a	NTNG1	ns	−0.856	ns	hsa-miR-26b	RNF138	ns	ns	0.829
hsa-miR-34a	PEG10	ns	−0.941	ns	hsa-miR-26b	SMAD2	ns	ns	0.816
hsa-miR-34a	RPRD1A	ns	−0.877	ns	hsa-miR-26b	SMAD4	ns	ns	0.933
hsa-miR-34a	SMAD4	−0.904	−0.904	ns	hsa-miR-26b	STX6	ns	ns	−0.858
hsa-miR-34a	SOCS6	−0.982	−0.994	ns	hsa-miR-26b	TECPR2	ns	ns	0.885
hsa-miR-34a	TMEM164	ns	0.88	ns	hsa-miR-26b	VPS4B	ns	ns	0.864
hsa-miR-34a	TNFRSF9	ns	0.882	ns	hsa-miR-342-3p	BARD1	ns	ns	0.835
hsa-miR-34a	TXNL1	ns	−0.931	ns	hsa-miR-342-3p	C18orf25	ns	ns	0.934
hsa-miR-34a	ZFYVE21	ns	−0.878	ns	hsa-miR-342-3p	EFNB2	ns	ns	0.866
hsa-miR-34a	ZNF3	ns	0.823	ns	hsa-miR-342-3p	IGFBP5	ns	ns	0.897
hsa-miR-378	KIF26A	0.848	ns	ns	hsa-miR-342-3p	KCTD12	ns	ns	0.923
hsa-miR-500	NEBL	ns	ns	−0.903	hsa-miR-342-3p	KIAA1468	ns	ns	0.834
hsa-miR-520e	C18orf25	ns	ns	−0.823	hsa-miR-342-3p	KIFAP3	ns	ns	−0.903
hsa-miR-520e	EFNB2	ns	ns	−0.813	hsa-miR-342-3p	LPPR4	ns	ns	0.872
hsa-miR-892b	BACH2	ns	0.813	ns	hsa-miR-342-3p	MEGF6	ns	ns	0.951

ns = not significant

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