Skip to main content

Table 2 Comparison of percentages of different types of aneuplodies detected by NGS and aCGH screening of the same WGA products in Phase I study

From: Randomized comparison of next-generation sequencing and array comparative genomic hybridization for preimplantation genetic screening: a pilot study

Parameters

NGS

aCGH

p

Total number of WGA products analyzed

164

164

 

Euploid % (n)

37.2 % (61)

37.2 % (61)

1.000a

Aneuploid % (n)

62.8 % (103)

62.8 % (103)

1.000a

Monosomy % (n)

19.4 % (20)

19.4 % (20)

1.000a

Trisomy % (n)

16.5 % (17)

16.5 % (17)

1.000a

Dual chromosomal abnormality % (n)

24.3 % (25)

24.3 % (25)

1.000a

Complex chromosomal abnormality % (n)

35.9 % (37)

37.8 % (39)

0.885a

Mosaicism % (n)

2.5 % (4)

1.2 % (2)

0.683b

  1. aby Chi-square analysis
  2. bby Fisher’s exact test