Randomized comparison of next-generation sequencing and array comparative genomic hybridization for preimplantation genetic screening: a pilot study

Table 3 Comparison of patient’s demographic parameters between NGS (Group A) and aCGH (Group B) in Phase II study

Parameters	NGS	aCGH	p
Total number of patients completed study	83	81
Mean female age ± SD	35.5 ± 3.3	35.2 ± 3.5	0.573
Mean D3 FSH (mUI/mL) ± SD	7.2 ± 1.6	7.1 ± 1.5	0.680
Mean AMH (ng/mL) ± SD	5.1 ± 2.1	4.6 ± 2.3	0.148
Mean E₂ (pg/mL) ± SD	25.7 ± 3.2	26.3 ± 3.6	0.261
Mean antral follicles ± SD	12.3 ± 3.0	12.8 ± 2.8	0.272
Mean sperm count (million/mL) ± SD	35.4 ± 4.5	36.1 ± 4.2	0.305
Mean sperm motility (%) ± SD	49.6 ± 15.1	48.5 ± 14.7	0.637

There is no significant difference in any of the parameters between the two groups (p >0.05, by t test)
SD Standard deviation, NS No significant difference between the two groups, FSH Follicle stimulation hormone, AMH Anti-Müllerian hormone, E₂ Estradiol

ISSN: 1755-8794