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Table 6 Comparison of screening results of each type of aneuploid blastocysts between NGS (Group A) and aCGH (Group B) in Phase II study

From: Randomized comparison of next-generation sequencing and array comparative genomic hybridization for preimplantation genetic screening: a pilot study

Parameters

NGS

aCGH

p

Total number of aneuploid blastocysts

249

247

 

Monosomy % (n)

21.7 % (54)

21.1 % (52)

0.950a

Trisomy % (n)

16.5 % (41)

17.8 % (44)

0.780a

Dual chromosomal abnormality % (n)

22.1 % (55)

23.1 % (57)

0.876a

Complex chromosomal abnormality % (n)

36.9 % (92)

36.8 % (91)

0.981a

Mosaicism % (n)

2.8 % (7)

1.2 % (3)

0.339b

  1. aby Chi-square analysis
  2. bby Fisher’s exact test