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Table 2 Categories of functionally enriched gene ontology (GO) biological processes (BPs) in the pink module. The latter is the cancer-associated module, and hub genes from this module are shown in the table
| Representative GO term | BP ID | Frequency (%) | Hypergeometric p-value | Genes in GO category |
|---|---|---|---|---|
| polyphosphate metabolic process | GO:0006797 | 0.001 | 5.789 × 10−03 | MINPP1 |
| cellular response to vitamin D | GO:0071305 | 0.040 | 2.153 × 10−05 | AHR, APP, ATP2C1, CXCL5, CYP27B1, DFNA5, DKK1, DUSP6, EGFR, FGD6, GLS, GNB5, HMGA2, HOXA1, IL8, IRS1, ITGB1, MET, MTMR2, MYO5A, PANX1, PSPH, PTHLH, PTPRK, RAB8B, SLC12A2, SLC20A1, SNAI2, STC1, STK3, TNFRSF10B |
| mitotic G2 phase | GO:0000085 | 0.013 | 1.156 × 10−03 | APP, E2F3 |
| regulation of single stranded viral RNA replication via double stranded DNA intermediate | GO:0045091 | 0.009 | 4.873 × 10−04 | AHR, APP, ATP2C1, CYP27B1, DFNA5, DKK1, DUSP6, E2F3, EGFR, FGD6, HMGA2, HOXA1, IL8, IRS1, ITGB1, LPCAT1, MET, MTMR2, PANX1, PLAG1, PTHLH, RAB8B, RSF1, SDC4, SLC20A1, SNAI2, STC1, STK3, TNFRSF10B |
| negative regulation of keratinocyte proliferation | GO:0010839 | 0.015 | 4.873 × 10−04 | APP, CXCL5, E2F3, EGFR, HMGA2, IRS1, ITGB1, MMP12, PLAG1, PTHLH, PTPRK, SNAI2 |
| gland morphogenesis | GO:0022612 | 0.399 | 2.716 × 10−05 | AHR, APP, ATP2C1, CHSY1, COL4A5, CYP27B1, DFNA5, DKK1, DUSP6, EGFR, FGD6, GNA12, HMGA2, HOXA1, IL8, IRS1, ITGB1, LAMA3, LAMC2, LPCAT1, MET, MINPP1, MMP10, MMP12, MTMR2, MYO5A, PLAG1, PTHLH, SEMA3C, SLC12A2, SNAI2, SNX10, STC1 |
