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Table 3 Key hub gene signatures based on an ensemble of centrality and trait relevance criteria (Gene significance [GS i GS] >0.2, scaled connectivity [K i ] 0.3, frequency [f] > 675)

From: Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell Carcinoma

Entrez ID Approved Gene Symbol Approved Gene Name Scaled connectivity (K i ) Gene significance (GS i GS) Frequency (f)
11335 CBX3 chromobox homolog 3 0.82 0.43 982
5723 PSPH phosphoserine phosphatase 0.37 0.32 980
27032 ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.91 0.40 948
29887 SNX10 sorting nexin 10 0.72 0.38 936
23531 MMD monocyte to macrophage differentiation-associated 0.57 0.37 936
79572 ATP13A3 ATPase type 13A3 0.74 0.38 929
2744 GLS glutaminase 0.70 0.37 923
1956 EGFR epidermal growth factor receptor 0.63 0.33 869
2768 GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.80 0.37 840
10257 ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.46 0.32 770
3149 HMGB3 high mobility group box 3 0.74 0.36 765
8091 HMGA2 high mobility group AT-hook 2 0.81 0.34 744
3198 HOXA1 homeobox A1 0.75 0.34 676