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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Design of a randomized controlled trial of disclosing genomic risk of coronary heart disease: the Myocardial Infarction Genes (MI-GENES) study

Fig. 1

Flow Diagram of the Proposed Clinical Trial. A flow diagram illustrating the design of the MI-GENES study. A total of 2026 individuals from the Mayo BioBank met the eligibility criteria. Among those 2026, a random sample of 1000 individuals was sent for screening genotyping. A total of 968 individuals had valid screening genotyping results. Recruitment was based on screening genotyping results in order to achieve the targeted enrollment goals of ~110 individuals with high GRS (≥1.1) and ~110 with average/low GRS (<1.1) with the expectation that approximately 10-20 study participants are likely to withdraw from the study or be lost to follow-up

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