Table 3 GO analysis of genes with attenuated expression in PR8-infected p53KO mice

GO:0002684

Positive regulation of immune system process

5

Ifng, Il2, Lag3, Stat6, Trat1

18

Blm, Lag3, Nfkbia, Il6, Fcer1g, Il15, Ifng, etc.

GO:0002682

Regulation of immune system process

8

Il2, Lag3, Orm1, Ifng, Trat1, Hmgb1, Jag1, Stat6

24

Blm, Orm1, Tnf, Nfkbia, Ifng, Tnfsf11, etc.

GO:0050900

Leukocyte migration

2

Ifng, Il16

6

Tnf, Ifng, Fcer1g, Il1b, Selp, Tlr2

GO:0045321

Leukocyte activation

7

Fyn, Ifng, Il2, Lag3, Stat6, Exo1, Mink1

20

Lag3, Blm, Fcgr2b, Was, Nfkbid, etc.

GO:0019882

Antigen processing and presentation

2

Ctse, Ifng

5

Ifng, Fcgr2b, Fcer1g, Slc11a1, Ctse

GO:0001776

Leukocyte homeostasis

2

Ifng, Il2

6

Ifng, Fcer1g, Gpam, Ikbkb, Il6, Pik3cd

GO:0002252

Immune effecter process

6

Ifng, Il2, Lag3, Stat6, Exo1, Irf7

17

Irf7, Tnf, Lag3, Fcgr2b, Fcer1g, Msh2, etc.

GO:0002253

Activation of immune response

1

Trat1

8

Nfkbia, Fcer1g, C1qb, Lat2, Plcg2, etc.

GO:0002200

Somatic diversification of immune receptors

4

Ifng, Il2, Stat6, Exo1

5

Ifng, Msh2, Cd40, Pms2, Exo1

GO:0002520

Immune system development

10

Hmgb1, Ifng, Il2, Jag1, Exo1, Tlx1, Six4

23

Blm, Timp1, Tnf, Tnfsf11, Cxcl13, Msh2, etc.

GO:0006955

Immune response

13

Ctla4, Cxcl1, Ifng, Mx2, Irf7, Polr3c, etc.

47

Irf7, Cxcl9, Cxcl10, Ccl2, Ccl7, etc.