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Table 6 The expression of selected cytokine and chemokine genes

From: Transcriptional analysis of immune-related gene expression in p53-deficient mice with increased susceptibility to influenza A virus infection

Gene symbol Gene description FCa (p53WT/p53KO)
3 dpi 6 dpi
Il1b interleukin 1 beta 2.30/3.71 2.85/0.93b
Il6 interleukin 6 3.27/2.79 2.52/0.95b
Il7 interleukin 7 0.65/0.47 0.34/0.83b
Il15 interleukin 15 2.64/1.72 2.05/0.67b
Il16 interleukin 16 4.93/0.15b 1.20/0.99
Il3ra interleukin 3 receptor, alpha chain 1.40/0.96 2.09/0.73b
Il10ra Interleukin 10 receptor, alpha (Il10ra), mRNA 3.04/3.16 4.14/1.21b
Il17rd interleukin 17 receptor D 0.48/0.41 0.07/0.45b
Il17re interleukin 17 receptor E 0.60/0.81 0.45/1.55b
Il20rb interleukin 20 receptor beta 0.27/0.98b 0.73/1.33
Ccl2 chemokine (C-C motif) ligand 2 (MCP-1) 11.83/130.82b 22.32/9.89b
Ccl3 chemokine (C-C motif) ligand 3 (MIP-1α) 7.90/11.23 9.62/1.90b
Ccl4 chemokine (C-C motif) ligand 4 (MIP-1β) 18.00/15.62 16.91/2.03b
Ccl7 chemokine (C-C motif) ligand 7 42.24/79.44 52.60/8.94b
Ccl11 chemokine (C-C motif) ligand 11 1.15/3.31 8.15/3.12b
Ccl19 chemokine (C-C motif) ligand 19 2.55/4.33 3.68/1.83b
Ccl25 chemokine (C-C motif) ligand 25 0.27/1.09b 0.58/1.53
Cxcl1 chemokine (C-X-C motif) ligand 1 21.07/6.71b 8.63/0.30b
Cxcl9 chemokine (C-X-C motif) ligand 9 39.58/120.08b 40.63/17.95b
Cxcl10 chemokine (C-X-C motif) ligand 10 (IP-10) 161.21/220.07 114.77/19.91b
Cxcl13 chemokine (C-X-C motif) ligand 13 2.48/10.71 7.60/1.71b
Cxcl14 chemokine (C-X-C motif) ligand 14 1.38/1.93 2.10/0.96b
Ccr6 chemokine (C-C motif) receptor 6 0.56/0.47 0.28/1.04b
Ccrl2 chemokine (C-C motif) receptor-like 2 2.89/2.26 2.35/0.82b
Tnf tumor necrosis factor 9.43/34.25b 8.90/1.06b
Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 0.46/2.18b 1.26/1.80
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.27/0.08 5.88/1.81b
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 5.86/1.08b 0.88/0.01b
Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 2.55/2.13 3.86/1.43b
  1. aFC fold change
  2. bsignificant difference in gene expression between PR8-infected p53WT and p53KO mice