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Table 6 The expression of selected cytokine and chemokine genes

From: Transcriptional analysis of immune-related gene expression in p53-deficient mice with increased susceptibility to influenza A virus infection

Gene symbol

Gene description

FCa (p53WT/p53KO)

3 dpi

6 dpi

Il1b

interleukin 1 beta

2.30/3.71

2.85/0.93b

Il6

interleukin 6

3.27/2.79

2.52/0.95b

Il7

interleukin 7

0.65/0.47

0.34/0.83b

Il15

interleukin 15

2.64/1.72

2.05/0.67b

Il16

interleukin 16

4.93/0.15b

1.20/0.99

Il3ra

interleukin 3 receptor, alpha chain

1.40/0.96

2.09/0.73b

Il10ra

Interleukin 10 receptor, alpha (Il10ra), mRNA

3.04/3.16

4.14/1.21b

Il17rd

interleukin 17 receptor D

0.48/0.41

0.07/0.45b

Il17re

interleukin 17 receptor E

0.60/0.81

0.45/1.55b

Il20rb

interleukin 20 receptor beta

0.27/0.98b

0.73/1.33

Ccl2

chemokine (C-C motif) ligand 2 (MCP-1)

11.83/130.82b

22.32/9.89b

Ccl3

chemokine (C-C motif) ligand 3 (MIP-1α)

7.90/11.23

9.62/1.90b

Ccl4

chemokine (C-C motif) ligand 4 (MIP-1β)

18.00/15.62

16.91/2.03b

Ccl7

chemokine (C-C motif) ligand 7

42.24/79.44

52.60/8.94b

Ccl11

chemokine (C-C motif) ligand 11

1.15/3.31

8.15/3.12b

Ccl19

chemokine (C-C motif) ligand 19

2.55/4.33

3.68/1.83b

Ccl25

chemokine (C-C motif) ligand 25

0.27/1.09b

0.58/1.53

Cxcl1

chemokine (C-X-C motif) ligand 1

21.07/6.71b

8.63/0.30b

Cxcl9

chemokine (C-X-C motif) ligand 9

39.58/120.08b

40.63/17.95b

Cxcl10

chemokine (C-X-C motif) ligand 10 (IP-10)

161.21/220.07

114.77/19.91b

Cxcl13

chemokine (C-X-C motif) ligand 13

2.48/10.71

7.60/1.71b

Cxcl14

chemokine (C-X-C motif) ligand 14

1.38/1.93

2.10/0.96b

Ccr6

chemokine (C-C motif) receptor 6

0.56/0.47

0.28/1.04b

Ccrl2

chemokine (C-C motif) receptor-like 2

2.89/2.26

2.35/0.82b

Tnf

tumor necrosis factor

9.43/34.25b

8.90/1.06b

Tnfrsf10b

tumor necrosis factor receptor superfamily, member 10b

0.46/2.18b

1.26/1.80

Tnfsf11

tumor necrosis factor (ligand) superfamily, member 11

0.27/0.08

5.88/1.81b

Tnfrsf8

tumor necrosis factor receptor superfamily, member 8

5.86/1.08b

0.88/0.01b

Tnfrsf18

tumor necrosis factor receptor superfamily, member 18

2.55/2.13

3.86/1.43b

  1. aFC fold change
  2. bsignificant difference in gene expression between PR8-infected p53WT and p53KO mice