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Fig. 4 | BMC Medical Genomics

Fig. 4

From: RNA sequencing from human neutrophils reveals distinct transcriptional differences associated with chronic inflammatory states

Fig. 4

Transcription factors (inner circle) identified by the IPA software analysis for differentially expressed genes in the comparison of neutrophil RNAseq data between AD and CRM juvenile idiopathic arthritis patients. IPA analysis elucidated12 TFs that are predicted to be inhibited (a) and 4 TFs predicted to be activated (b). Each TF is connected with its target genes; dashed and solid connecting lines indicate an indirect or direct relationship with the master regulator respectively. The colors of the lines connecting TFs and their corresponding targets indicate the predicted activation (orange) or inhibition (blue) status

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