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Table 1 Clinical characteristics by cohort for samples used for algorithm training

From: Development and verification of the PAM50-based Prosigna breast cancer gene signature assay

Characteristic BC no AST WashU UNC BC TAM
Median Follow Up (Years) 11.9 NA NA 12.1
Patient Age     
 Mean 59.9 59.3 56.5 66.3
 Stdev 13.8 15.2 15.9 9.6
Premenopausal     
 Yes 81 0 0 10
 No 214 0 0 219
 Unknown 9 118 92 3
ER Status     
 Positive 203 65 47 232
 Negative 99 48 30 0
 Unknown 2 5 15 0
Node Status     
 Positive 18 57 41 0
 Negative 276 58 35 232
 Unknown 10 3 16 0
HER2 Status     
 Positive 44 31 21 19
 Negative 253 59 51 210
 Unknown 7 28 20 3
PR Status     
 Positive 138 50 34 130
 Negative 139 63 38 86
 Unknown 27 5 20 16
Tumor Size     
 ≤2 193 87 24 149
 >2 111 29 49 83
 Unknown 0 2 19 0
Grade     
 1 26 5 10 15
 2 127 32 20 103
 3 145 78 43 108
 Unknown 6 3 19 6
  1. Any missing values were not available or not collected and therefore not reportable
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