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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Genome instability model of metastatic neuroblastoma tumorigenesis by a dictionary learning algorithm

Fig. 1

An aCGH signal before and after segmentation. An aCGH profile can be thought of as the concatenation of the log-ratio values ordered by chromosomes and by chromosomal location. In the top plot, each black dot corresponds to a probe placed at a given chromosomal location (x-axis) and with a corresponding estimated a log-ratio of the CNAs for the hybridized control and patient (y-axis). Probes are sorted according to their chromosomal location, as example, from chromosome 1 to chromosome 4 and each dotted red line represents boundaries among chromosomes. The bottom plot shows the same aCGH profile after segmentation. The thin black line is a piecewise constant signal obtained as a result of the segmentation. The red dots indicate gain whereas the green dots correspond to probes where a loss occurred

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