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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

Fig. 1

a Approximate area proportional Venn diagram with overlaps of the differentially expressed genes of the four individually analyzed datasets under the same threshold (|FCH| ≥ 2, FDR ≤ 0.05). b Ingenuity Canonical Pathway overrepresentations compared between this MADAD transcriptome and the included dataset from Khattri et al. 2014 (GSE58558). The bars represent –log10 transformed Benjamini-Hochberg adjusted p-values termed –log(FDR), and the red threshold line indicates the FDR ≤ 0.05 cut-off. c Cutaneous localization of the MADAD transcriptome as compared to the epidermis and dermis related genes defined by Esaki et al. [63]

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