SYMBOL | LAYER | logFCH (MAD-AD) | logFCH (Dupilumab, 300 mg, W4) | logFCH (Cyclosporin, W2) | logFCH (Cyclosporin, W12) | logFCH (UVB, W12) | Genename | Recovery (Dupilumab, 300 mg, W4) | Recovery (Cyclosporin, W2) | Recovery (Cyclosporin, W12) | Recovery (UVB, W12) |
---|---|---|---|---|---|---|---|---|---|---|---|
IGFL1 | E | 3.5 | −2.4a | −2.6a | −3.6a | −2.3a | IGF-like family member 1 | 68.60 | 74.81 | 101.60 | 64.33 |
OASL | D | 2.9 | −2.7a | −2.7a | −3.3a | −1.8a | 2'-5'-oligoadenylate synthetase-like | 93.07 | 93.24 | 112.20 | 60.33 |
SELE | D | 2.4 | −2.9a | −1.6a | −1.6a | −2.3a | selectin E | 121.06 | 66.99 | 66.24 | 94.94 |
AKR1B10 | E | 3.2 | −1.3 | −3.2a | −4.0a | −3.0a | aldo-keto reductase family 1, member B10 (aldose reductase) | 42.39 | 100.29 | 127.48 | 95.22 |
MS4A14 | D | 1.4 | −2.0a | −1.2a | −1.4a | 0.0 | membrane-spanning 4-domains, subfamily A, member 14 | 149.43 | 84.71 | 102.42 | 0.00 |
NUF2 | E | 1.4 | −2.2a | −1.4a | −1.4a | −0.9 | NUF2, NDC80 kinetochore complex component | 155.33 | 96.79 | 96.65 | 59.46 |
S100A9 | E | 3.8 | −1.1 | −3.7a | −4.5a | −2.2a | S100 calcium binding protein A9 | 27.95 | 96.75 | 116.47 | 57.26 |
SERPINB3 | E | 3.8 | −1.9 | −3.2a | −3.8a | −2.4a | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 50.29 | 85.47 | 101.40 | 62.98 |
C15orf48 | E | 1.0 | −0.9 | −1.0 | −1.3a | −2.1a | chromosome 15 open reading frame 48 | 93.70 | 103.85 | 131.53 | 211.69 |
MMP3 | D | 1.1 | −4.0a | −2.0a | −0.9 | −0.3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 374.65 | 181.39 | 81.06 | 25.91 |
MUC7 | −1.2 | −0.1 | 0.0 | 0.0 | 1.1 | mucin 7, secreted | −9.82 | 0.00 | 0.00 | 87.60 | |
HSPB7 | D | −1.6 | 1.6 | 0.6 | 1.7a | 0.2 | heat shock 27 kDa protein family, member 7 (cardiovascular) | 102.98 | 37.95 | 107.88 | 13.51 |
SCGB1D2 | D | −1.2 | 0.3 | 0.5 | 1.2a | 0.0 | secretoglobin, family 1D, member 2 | 25.96 | 43.28 | 100.97 | 0.00 |
BTC | E | −2.1 | −0.1 | 1.0 | 1.3a | 1.3a | betacellulin | −6.53 | 48.15 | 65.56 | 65.17 |
CIDEC | −1.7 | 2.1 | 1.2a | 1.8a | 0.0 | cell death-inducing DFFA-like effector c | 126.22 | 72.11 | 106.23 | −2.38 | |
HSD11B1 | E | −2.3 | −1.8 | 0.1 | 2.1a | 1.0a | hydroxysteroid (11-beta) dehydrogenase 1 | −77.60 | 5.69 | 91.93 | 44.65 |
PLIN1 | −1.9 | 1.9 | 1.7a | 2.0a | 0.3 | perilipin 1 | 98.89 | 85.20 | 103.82 | 12.83 | |
SCGB2A1 | D | −1.8 | −0.1 | 0.9 | 1.7a | 1.5a | secretoglobin, family 2A, member 1 | −7.33 | 50.36 | 92.70 | 80.79 |
WIF1 | D | −2.2 | 0.7 | 1.2 | 2.1a | 1.3a | WNT inhibitory factor 1 | 29.58 | 52.56 | 92.11 | 58.40 |
E = Epidermis, D = Dermis (Esaki et al. [63]) | Average | 76.78 | 72.61 | 94.64 | 57.51 |