Fig. 2
From: RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease
Unsupervised hierarchical clustering of comprehensive microRNA sequencing reads using the Pearson correlation method results in independent clustering of Dupuytren’s and control palmar fascia. Only a single adjacent fascia specimen clustered with the Dupuytren’s fascia indicating that visual inspection alone may not be reliable in distinguishing between diseased and non-diseased fascia. These data show that microRNA expression patterns may be able to differentiate between diseased and non-diseased fascia and may play key roles in driving pathogenic fibrosis