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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study

Fig. 2

Associations of miRNAs and direction of effect. The effect direction is shown for each miRNA significantly associated with age, BMI and sex after adjustment for a) technical covariates and the respective other two phenotypes and b) after additional adjustment for blood composition. Each row represents a miRNA and each column shows the association with a specific phenotype. The magnitude of the Benjamini-Hochberg corrected p-values (q-values) is indicated by the colour tone. Darker colour indicates a lower q-value. Positive correlations of miRNA levels (β∆Ct < 0, since smaller ∆Ct values indicate higher miRNA levels) are indicated by red upward triangles while negative correlations (β∆Ct > 0, since larger ∆Ct values indicate lower miRNA levels) are indicated by blue downward triangles. Sex has been numerically encoded as the number of X-chromosomes. Hence, positive correlation here indicates a female-specific miRNA while negative correlation indicates a male-specific miRNA. A grey dot indicates no significant association

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